Reduced sperm function on sulfasalazine



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Infertility in men with inflammatory bowel disease

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INTRODUCTION

best of Sulfasalazine function on Reduced sperm
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1 May The sperm motility and acrosome reaction, which are important for fertilization, were significantly reduced by SASP. Furthermore, to investigate.

Reduced sperm function on sulfasalazine

Reduced sperm function on sulfasalazine
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Description:Advanced Search Abstract Sulfasalazine SASP has been reported to depress the fertility in men and experimental male animals, but the fundamental mechanisms of infertility caused by SASP are still unknown. The sperm motility and acrosome reaction, which are important for fertilization, were significantly reduced by SASP. It was revealed that CD59, which is located on the acrosomal membrane and is known to be important for the reproductive function of sperm, was affected in the testes; this was also confirmed by real-time PCR analysis, but the spermatogenesis-related genes examined in this study were not affected. Therefore, we focused on CD59 and two other acrosome membrane related-genes:

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Views: 6702 Date: 2018-08-23 Favorited: 56 favorites

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